Polymorphism of human CD1 genes

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چکیده

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polymorphism in exon 2 of cd1 genes in southwest of iran.

the cd1 family is less variable transmembrane antigen presenting molecules related to the mhc molecules. cd1a and cd1e genes are the most polymorphic ones associated with autoimmune diseases. the aim was to better clarify the map of cd1 genes in southwest iranian normal population for implications in vaccine design.in this study we investigated the polymorphism of cd1a, cd1d and cd1e in 311 hea...

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Polymorphism in Exon 2 of CD1 Genes in Southwest of Iran

BACKGROUND The CD1 family is less variable transmembrane antigen presenting molecules related to the MHC molecules. CD1a and CD1e genes are the most polymorphic ones associated with autoimmune diseases. The aim was to better clarify the map of CD1 genes in Southwest Iranian normal population for implications in vaccine design. METHODS In this study we investigated the polymorphism of CD1a, CD...

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Group 1 CD1 genes in rabbit.

CD1 is an Ag-presenting molecule that can present lipids and glycolipids to T cells. The CD1 genes were first identified in the human, and since then, homologs have been identified in every mammalian species examined to date. Over a decade ago, CD1B and CD1D homologs were identified in the rabbit. We have extended this earlier study by identifying additional CD1 genes with the goal of developin...

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Polymorphism of Genes and Implantation Failure

Implantation failure is the most frequent cause of pregnancy loss in couples who try to conceive, either in a natural way or using assisted reproductive techniques (ART). Identify the precise mechanisms of implantation failure can lead to identify couples at risk and also providing appropriate therapeutic options to affected couples. Despite the high prevalence of this disorder, a few causing f...

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Polymorphisms of CD1 genes in chronic dysimmune neuropathies.

CD1 are MCH-like glycoproteins specialized in capturing and presenting glycolipid to T cells. Expression of CD1 molecules has been observed on endoneurial machrophages in patients with chronic inflammatory demyelinating polyneuropathy (CIDP) and vasculitis and polymorphisms of CID1A and CD1E genes have been associated with susceptibility to develop Guillain-Barré syndrome. In 46 patients with C...

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ژورنال

عنوان ژورنال: Tissue Antigens

سال: 1999

ISSN: 0001-2815,1399-0039

DOI: 10.1034/j.1399-0039.1999.540202.x